✦ NRC is a newly discovered nicotinamide adenine dinucleotide (NAD+) precursor vitamin. 1

✦ NRC is emerging as a leading candidate due to its bioavailability, safety, and strong ability to raise NAD+ content compared to other precursors. 2

✦ NAD+ is an essential coenzyme that plays important roles in various metabolic pathways and has recently gained much attention for its potential to rescue female reproduction in mammals. 2, 3

✦ CoQ10 is one of the most powerful fat-soluble antioxidants in the body. 4

✦ After the age of 35 to 40 years, humans slowly begin to lose their ability to synthesise CoQ10. 5

✦ Ubidecarenone remains the most studied form of COQ10. 4

✦ LipiSperse® is a patented delivery technology that uses cold water dispersion technology (CWD) allowing solid/powder lipophilic active ingredients such as CoQ10 and increases their bioavailability and uptake in the body.

✦ It has recently gained a lot of attention for its role in improving oocyte quality and counteracting oocyte ageing. 6

✦ It also has the potential of improving IVF-ICSI cycles, with a randomised controlled double blinded study finding pretreatment with CoQ10 improves ovarian response to stimulation and embryological parameters in young women with poor ovarian reserve. 7

✦CoQ10 supplementation significantly improves semen parameters in men. 8

✦ Contains Zn glycinate, which is a highly absorbable organic form.

✦ Zinc is required by many antioxidant enzymes. 9

In females:

✦ Zinc has specific antioxidant properties required for the reproductive system and protects the oocytes from free radicals and reactive oxygen species. 9

✦ Zinc contributes to normal fertility and reproduction. Zinc is essential for reproduction. 9

✦ It is necessary for the metabolism of reproductive hormones, ovulation, fertilisation and the health of the mother and foetus during pregnancy. 10

In Males:

✦ Zinc is used in virtually every aspect of male reproduction, including the hormone metabolism. 5

✦ Zinc status appears to represent an important determinant of serum total testosterone levels. 5

✦ Zinc is essential for reproduction, testicular function, the formation, and maturation of sperm. 9, 10

✦ We use an organic form of Se, selenomethionine.

✦ Selenium is an essential trace element.

✦ Se acts as an antioxidant, is essential for call protection from free radicals and also plays a role in thyroid metabolism and immune regulation. 11

In males:

✦ Selenium is required for normal sperm maturation and sperm motility. 9

✦ Selenium contributes to normal spermatogenesis. 12

✦ Selenium is a critical antioxidant that is essential for male fertility because of its role in testosterone synthesis, normal sperm maturation, and motility; moreover, clinical trials reveal that selenium has the ability to increase sperm motility and assist in the production of healthy spermatozoa. The tail of the sperm relies on adequate selenium status to maintain its “whip-like” action. 5

For thyroid:

✦ Selenium is required for normal thyroid hormone synthesis, activation and metabolism. 9